Distribution and quantitative analysis of CIDEa and CIDEc in broiler chickens: accounting for differential fat deposition between strains     

J. Z. Huang  L. M. Huang  Q. J. Zeng  E. F. Huang  H. P. Liang  Q. Wei 《British poultry science》2018,59(2):173-179

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Preparation,characterization, and pharmacokinetics in swine of a florfenicol enteric formulation prepared using hot‐melt extrusion technology          下载免费PDF全文

Y. Xu  X. Wen  X. Feng  Z. Liang  X. Ye  H. Nie  X. Liao  J. Li  Y. Zeng  S. Tang  J. He 《Journal of veterinary pharmacology and therapeutics》2018,41(4):572-580

The objective of this work was to manufacture an enteric formulation of florfenicol (FF) using hot‐melt extrusion (HME) technology and to evaluate its in vitro dissolution and in vivo pharmacokinetics. For the HME process, hypromellose acetate succinate LG (HPMCAS‐LG) was the enteric polymer mixed with FF, and the two components were extruded with a standard screw configuration at a speed of 50 rpm. Differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), powder X‐ray diffraction (PXRD), and Fourier transform infrared spectroscopy (FT‐IR) were performed to characterize the HME extrudate. The release percentage of the enteric formulation in the acidic stage was <10% of the loaded FF, whereas that in the phosphate buffer stage was >80%. Pharmacokinetic evaluations in swine revealed that the enteric formulation had a longer t_1/2λ and MRT than commercially available FF powder (FULAIKA^®), indicating that the novel formulation exhibited enteric and sustained release properties. Compared with the commercial product, the relative bioavailability of the enteric formulation reached up to 117.2%. This study suggests that this formulation may have potential for future commercialization.  相似文献   

青藏高原东部乡土植物对高寒沙化草地土壤性质的影响   总被引：1，自引：0，他引：1  

张潇喜  曾凯  蔡义民  马赛男  宋洋  刘琳  陈冬明  周春梅  孙飞达  陈有军 《草业科学》2018,35(4):749-759

以青藏高原东部高寒沙化草地为研究对象,通过比较分析狭叶红景天(Rhodiola rosea)、硬秆仲彬草(Kengyilia rigidula)、垂穗披碱草(Elymus nutans)和高山红柳(Salix cupularis)4种乡土植物对沙化草地的土壤理化性质、土壤酶活性及微生物生物量的影响,旨在为高寒草地沙化地生态植被的重建与恢复选择适宜的治理植物提供理论依据。结果显示:1)种植4种植物治理恢复5年后,土壤含水量均有显著升高(P0.05),土壤容重和土壤pH有不同程度的下降,垂穗披碱草处理下土壤含水量最高,与对照相较增加了357.70%;2)植被恢复显著提高了土壤中与碳氮磷循环相关的各种酶的活性(P0.05),其中狭叶红景天样地中的土壤纤维素酶、过氧化物酶、蔗糖酶、蛋白酶和磷酸酶活性最高,分别为对照的3.19、1.98、3.22、1.87和4.59倍。3)种植4种植物治理恢复5年后,不同土壤微生物生物量碳(MBC)、微生物生物量氮(MBN)均有显著提高(P0.05),狭叶红景天的MBC、MBN和微生物生物量碳氮比(MBC/MBN)均为最高,分别为对照的4.39、3.46和1.27倍;4)种植狭叶红景天和高山红柳样地,土壤酶活性与土壤理化性质及微生物生物量呈极显著(P0.01)和显著(P0.05)相关,种植垂穗披碱草样地,土壤酶活性与土壤理化性质及微生物生物量相关性较差。研究表明,4种植物种植5年后,狭叶红景天对高寒沙化草地的土壤特性改善更明显。  相似文献   

镉胁迫对茶园绿肥槐叶决明“茶肥1号”的生长及吸收积累的影响     

向芬  李维  刘红艳  周凌云  丁玎  曾振 《草业科学》2018,35(7):1679-1684

以槐叶决明(Cassia sophera)"茶肥1号"为材料,采用盆栽法研究了不同浓度(0、5、10、20、40、80、120、160mg·kg~(-1))镉(Cd)胁迫对"茶肥1号"生长及Cd吸收积累特性的影响。结果表明:土壤中添加0~160mg·kg~(-1) Cd,随Cd胁迫浓度的增加,各器官生长量受到明显抑制。"茶肥1号"各器官Cd含量与Cd胁迫浓度、土壤有效态Cd含量均呈显著正相关关系(P0.05),各器官Cd积累量顺序为根茎叶。土壤中Cd元素大部分被根固定,向地上部运输的比例较低,说明"茶肥1号"植株根部最易受到Cd毒害。随着Cd浓度的增加,"茶肥1号"的种子Cd累积量增加缓慢。本研究在较高的Cd胁迫浓度条件下,"茶肥1号"在较短的时期内对Cd具有明显的富集作用,其根、茎、叶中浓度分别为113.85、20.15、7.00mg·kg~(-1)。因此,"茶肥1号"可作为土壤修复类的植物,在污染地区种植,对环境保护与田地污染治理有重要的意义。  相似文献   

Lactobacillus plantarum BS22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1          下载免费PDF全文

Y. Zeng  D. Zeng  Y. Zhang  X. Q. Ni  J. Wang  P. Jian  Y. Zhou  Y. Li  Z. Q. Yin  K. C. Pan  B. Jing 《Journal of animal physiology and animal nutrition》2018,102(1):e449-e459

Probiotics promote the health of the host by maintaining intestinal microbial homeostasis. This study aimed to investigate the benefits of Lactobacillus plantarum BS22 (LP) in the gastrointestinal tract (GIT) microbial homeostasis of broiler chickens exposed to aflatoxin B₁ using the PCR‐DGGE, viable count and real‐time PCR. The toxin adsorption experiment demonstrated that treatment R5 (1.0 × 10⁸ CFU/g LP) exhibited good absorptive effect in adsorbing the aflatoxin B₁ (AFB₁) in vitro. DGGE showed that the composition and structure of gut microbiota were more similar in the mucosa than in the content of all the samples. In addition, higher diversity of the microbiota was observed in the caecum and glandular stomach than in other segments. Lactobacillus, Enterococcus and Enterobacteriaceae were more abundant in the ileum than in the other segments. Enterobacteriaceae in groups I (basal diet) and II (basal diet+50 μg/kg AFB₁) showed a significant difference in group III (basal diet + 50 μg/kg AFB₁ + 1 × 10⁸ CFU/g LP) in the crop content and duodenum mucosa (p < .05). This investigation indicates that the L. plantarum BS22 promotes GIT microbial homeostasis in broiler chickens exposed to AFB₁, particularly for the intestine mucosa microbiota. Thus, L. plantarum BS22 is a possible candidate for degrading AFB_1.  相似文献   

Intracellular calcium chelating agent (BAPTA‐AM) aids stallion semen cooling and freezing–thawing          下载免费PDF全文

Shuaishuai Wu  Igor F. Canisso  Weigang Yang  Ihteshamu Ul Haq  Qiang Liu  Ying Han  Shenming Zeng 《Reproduction in domestic animals》2018,53(5):1235-1242

This study aimed to investigate the effects of different concentrations of 1,2‐bis‐(o‐aminophenoxy)‐ethane‐N,N,N0 N0‐tetraacetic acid, tetra‐acetoxymethyl ester (BAPTA‐AM), an intracellular calcium chelating agent, on stallion semen cooling and freezing–thawing. After collection, semen was extended (1:1 v/v) on a skim milk‐based extender, centrifuged and resuspended at 400 million/ml into cooling or freezing extenders containing 0, 5, 25, 50, 100 and 200 μΜ BAPTA‐AM. Motility parameters were assessed after cooling in Equitainer at 5°C for 12, 24, 48, 72 and 120 hr and after freezing–thawing. In addition, mitochondrial membrane potential, intracellular ATP, reactive oxygen species and malondialdehyde concentrations were measured in cryopreserved‐thawed semen. Cooled stored (48 hr) semen containing 50 μΜ BAPTA‐AM and control extender (0 μΜ BAPTA‐AM) was used to assess fertility. Inclusion of 50 μΜ BAPTA‐AM resulted in superior sperm motility parameters during cooled storage when compared to other groups (p < 0.05). Furthermore, semen cryopreserved in extender containing 50 μΜ BAPTA‐AM showed increased intracellular ATP and mitochondrial membrane potential, whereas reactive oxygen species and malondialdehyde were increased after thawing for all groups (p < 0.05). Addition of 50 μΜ BAPTA‐AM to cooling extender resulted in similar pregnancy rates to the control group (75% vs. 73.6%, respectively; p > 0.05). In conclusion, the addition of BAPTA‐AM to semen extenders aided stallion semen cryopreservation in a dose‐dependent manner. Furthermore, the cooling extender supplemented with 50 μΜ BAPTA‐AM could be used to prolong the sperm motility during cooling without apparently compromising fertility. Field trials should be conducted to assess fertility of cryopreserved stallion semen with BAPTA‐AM.  相似文献   

一批早熟棉花材料在江西的表现与分析     

肖水平  杨绍群  孙亮庆  刘新稳  曾小林  柯兴盛 《江西棉花》2015,(3)

为选育适宜江西棉区种植的早熟棉品种，实行棉花生产机械化，并大力推行棉田两熟或多熟种植模式，以稳定江西植棉面积，提高棉田效益。江西省棉花研究所于2013年在其科研基地对征集引进的26份早熟棉花材料进行鉴定。结果表明：该批材料早熟性整体表现较好，抗棉铃虫性较好，单株成铃数变幅较大。经综合比较分析，筛选出综合表现较好、性状特征较符合机采要求的WH1、邯郸686和抗虫花株3份材料，可重点加以利用。  相似文献   

赣州市湿加松引种栽培调查     

郭赋英  曾洪流  楼浙辉 《江西林业科技》2015,(1):25-27

通过赣州市引种湿加松的调查分析,提出合理化的引种栽培建议。  相似文献   

丙酸钙及其在动物生产中的应用     

殷燕  李晨博  曾晔临  王恬 《饲料工业》2011,32(16)

丙酸钙是一种新型饲料添加剂,近年来在饲料生产、动物生产中的应用越来越广泛。作为一种有机酸盐,丙酸钙不仅作为防腐剂,也常常作为酸化剂在饲料工业中应用,对预防疾病与提高动物生产性能发挥了积极的作用。文中综述了丙酸钙的理化性质与功用,对反刍动物产奶量、消化代谢与代谢疾病预防的影响及其在家禽生产中的应用。  相似文献   

Dissecting combining ability effect in a rice NCII-III population provides insights into heterosis in <Emphasis Type="Italic">indica-japonica</Emphasis> cross     

Hao Zhou  Duo Xia  Jing Zeng  Gonghao Jiang  Yuqing He 《Rice》2017,10(1):39

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